Member

Furutani-Seiki Makoto

  • PI
School of Medicine, Yamaguchi University
Professor
Research Areas
Developmental & Regeneration biology
Keywords
Regeneration, YAP mechano-homeostasis, cell-tension, gravity

Related Outline

Career

Ph.D: The University of Tokyo, Faculty of Medicine
Assistant Professor: The University of Tokyo, Faculty of Medicine, Immunology
Postdoc: Max-Planck-Institut für Entwicklungsbiologie (Germany)
PI: Freiburg University, Institut für Biologie (Germany), PRESTO (JST) researcher
Group leader: ERATO Kondoh Differentiation Signaling project
Professor: Kumamoto University, Institute of Resource Development and Analysis.
PI: University of Bath, Institute for Regenerative Medicine.
Professor: Graduate School of Medicine, Yamaguchi University.

Representative Achievements

  • Gravity sensing in plant and animal cells.
    Takahashi K, Takahashi H, Furuichi T, Toyota M, Furutani-Seiki M, Kobayashi T, Watanabe-Takano H, Shinohara M, Numaga-Tomita T, Sakaue-Sawano A, Miyawaki A, Naruse K.
    NPJ Microgravity, 2021
    DOI: 10.1038/s41526-020-00130-8
  • ARHGAP29 expression may be a novel prognostic factor of cell proliferation and invasion in prostate cancer
    Shimizu K, Matsumoto H, Hirata H, Ueno K, Samoto M, Mori J, Fujii N, Kawai Y, Inoue R, Yamamoto Y, Yano S, Shimabukuro T, Furutani-Seiki M, Matsuyama H.
    Oncol Rep. 2020
    DOI: https://doi.org/10.3892/or.2020.7811
  • YAP mediated mechano-homeostasis – conditioning 3D animal body shape.
    Asaoka Y, Furutani-Seiki M.
    Curr Opin Cell Biol. 2017
    DOI: https://doi.org/10.1016/j.ceb.2017.11.013
  • Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells.
    Cravo AS, Carter E, Erkan M, Harvey E, Furutani-Seiki M, Mrsny R.
    Tissue Barriers. 2015
    DOI: https://doi.org/10.1080/21688370.2015.1037948
  • YAP is essential for tissue tension to ensure vertebrate 3D body shape.
    Porazinski S, Wang H, Asaoka Y, Behrndt M, Miyamoto T, Morita H, Hata S, Sasaki T, Krens SFG, Osada Y, Asaka S, Momoi A, Linton S, Miesfeld JB, Link BA, Senga T, Shimizu N, Nagase H, Matsuura S, Bagby S, Kondoh H, Nishina H, Heisenberg CP, Furutani-Seiki M.
    Nature. 2015
    DOI: https://doi.org/10.1038/nature14215
  • YAP and TAZ regulate skin wound healing.
    Lee MJ, Byun MR, Furutani-Seiki M, Hong JH, Jung HS.
    J Invest Dermatol. 2014
    DOI: https://doi.org/10.1038/jid.2013.339
  • A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes.
    Furutani-Seiki M, Sasado T, Morinaga C, Suwa H, Niwa K, Yoda H, Deguchi T, Hirose Y, Yasuoka A, Henrich T, Watanabe T, Iwanami N, Kitagawa D, Saito K, Asaka S, Osakada M, Kunimatsu S, Momoi A, Elmasri H, Winkler C, Ramialison M, Loosli F, Quiring R, Carl M, Grabher C, Winkler S, Del Bene F, Shinomiya A, Kota Y, Yamanaka T, Okamoto Y, Takahashi K, Todo T, Abe K, Takahama Y, Tanaka M, Mitani H, Katada T, Nishina H, Nakajima N, Wittbrodt J, Kondoh H.
    Mech Dev. 2004
    DOI: https://doi.org/10.1016/j.mod.2004.04.016
  • Medaka and zebrafish, an evolutionary twin study.
    Furutani-Seiki M, Wittbrodt J.
    Mech Dev. 2004
    DOI: https://doi.org/10.1016/j.mod.2004.05.010
  • Single cell lineage and regionalization of cell populations during Medaka neurulation.
    Hirose Y, Varga ZM, Kondoh H, Furutani-Seiki M.
    Development. 2004
    DOI: https://doi.org/10.1242/dev.01140
  • Neural degeneration mutants in the zebrafish, Danio rerio.
    Furutani-Seiki M, Jiang YJ, Brand M, Heisenberg CP, Houart C, Beuchle D, van Eeden FJ, Granato M, Haffter P, Hammerschmidt M, Kane DA, Kelsh RN, Mullins MC, Odenthal J, Nüsslein-Volhard C.
    Development. 1996
    DOI: https://doi.org/10.1242/dev.123.1.229